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CD86 ANTIGENS
Descriptors Found:
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DeCS
Descriptor
English
:
Antigens, CD86
Descriptor
Spanish
:
Antígenos CD86
Descriptor
Portuguese
:
Antígenos CD86
Synonyms
English
:
B7-2 Costimulatory Molecule
CD86 Antigens
Tree Number:
D12.776.467.150.200
D12.776.543.095.200
D23.050.301.264.035.276.200
D23.050.301.285.200
D23.101.100.110.276.200
D23.529.168.200
Definition
English
:
A costimulatory ligand expressed by
ANTIGEN-PRESENTING CELLS
that binds to CD28 ANTIGEN with high specificity and to
CTLA-4 ANTIGEN
with low specificity. The interaction of CD86 with CD28 ANTIGEN provides a stimulatory signal to
T-LYMPHOCYTES
, while its interaction with
CTLA-4 ANTIGEN
may play a role in inducing
PERIPHERAL TOLERANCE.
History Note
English
:
2006(1993)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
51076
Unique Identifier:
D051940
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS